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Generally, ribavirin inhibits the host enzyme inosine monophosphate dehydrogenase to lower the guanosine triphosphate level. This whole mechanism is an important part of the virus copy. This decreases the intracellular pool of guanosine triphosphate, a building block for viral RNA. It slows the replication.

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Uses of Ribavirin

The uses given below are possible with the Ribavirin medicine (Brand name Ribaviz)

Chronic hepatitis C may be treated with Ribavirin.

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Daclatasvir works by inhibiting the HCV NS5A protein, a crucial component for hepatitis C virus (HCV) replication and assembly. It binds to the N-terminus within NS5A's Domain 1, thereby disrupting the formation of the viral replication complex and preventing the assembly of new viral particles. This dual action of inhibiting both viral RNA replication and virion assembly leads to a significant reduction in viral load.

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